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Dynamics of enhancer chromatin signatures mark the transition from pluripotency to cell specification during embryogenesis
The generation of distinctive cell types that form different tissues and organs requires precise, temporal and spatial control of gene expression. This depends on specific cis-regulatory elements distributed in the noncoding DNA surrounding their target genes. Studies performed on mammalian embryoni...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460198/ https://www.ncbi.nlm.nih.gov/pubmed/22593555 http://dx.doi.org/10.1101/gr.134833.111 |