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Transcription factor binding at enhancers: shaping a genomic regulatory landscape in flux

The mammalian genome is packed tightly in the nucleus of the cell. This packing is primarily facilitated by histone proteins and results in an ordered organization of the genome in chromosome territories that can be roughly divided in heterochromatic and euchromatic domains. On top of this organizat...

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Detalles Bibliográficos
Autores principales: Palstra, Robert-Jan, Grosveld, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460357/
https://www.ncbi.nlm.nih.gov/pubmed/23060900
http://dx.doi.org/10.3389/fgene.2012.00195