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Transcription factor binding at enhancers: shaping a genomic regulatory landscape in flux
The mammalian genome is packed tightly in the nucleus of the cell. This packing is primarily facilitated by histone proteins and results in an ordered organization of the genome in chromosome territories that can be roughly divided in heterochromatic and euchromatic domains. On top of this organizat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460357/ https://www.ncbi.nlm.nih.gov/pubmed/23060900 http://dx.doi.org/10.3389/fgene.2012.00195 |