Transcriptional regulation of BRCA1 expression by a metabolic switch

Though the linkages between germline mutations of BRCA1 and hereditary breast cancer are well known, recent evidence suggests that altered BRCA1 transcription may also contribute to sporadic forms of breast cancer. Here we show that BRCA1 expression is controlled by a dynamic equilibrium between tra...

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Detalles Bibliográficos
Autores principales: Di, Li-Jun, Fernandez, Alfonso G., De Siervi, Adriana, Longo, Dan L., Gardner, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460552/
https://www.ncbi.nlm.nih.gov/pubmed/21102443
http://dx.doi.org/10.1038/nsmb.1941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460552/
https://www.ncbi.nlm.nih.gov/pubmed/21102443
http://dx.doi.org/10.1038/nsmb.1941

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