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Mitogen activated protein kinase phosphatase-1 prevents the development of tactile sensitivity in a rodent model of neuropathic pain

BACKGROUND: Neuropathic pain due to nerve injury is one of the most difficult types of pain to treat. Following peripheral nerve injury, neuronal and glial plastic changes contribute to central sensitization and perpetuation of mechanical hypersensitivity in rodents. The mitogen activated protein ki...

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Detalles Bibliográficos
Autores principales: Ndong, Christian, Landry, Russell P, DeLeo, Joyce A, Romero-Sandoval, Edgar Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460752/
https://www.ncbi.nlm.nih.gov/pubmed/22540262
http://dx.doi.org/10.1186/1744-8069-8-34