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TLR9-mediated ARF6 activation is involved in advancing CpG ODN cellular uptake

Nucleic acid cellular uptake into endosomes is critical in eliciting nucleotide-sensing toll-like receptors (TLRs) innate immune responses. ADP-ribosylation factor 6 (ARF6) is a member of the Ras superfamily, which is critical to a wide variety of cellular events including endocytosis. Our previous...

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Detalles Bibliográficos
Autores principales: Wu, Jing-Yiing, Kuo, Cheng-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460832/
https://www.ncbi.nlm.nih.gov/pubmed/23060951
http://dx.doi.org/10.4161/cib.20182