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Assessing developmental roles of MKK4 and MKK7 in vitro

In vivo gene knockout studies in mice have revealed essential roles of the mitogen-activated protein kinases (MAPKs) in embryogenesis, but due to early lethality of the knockout embryos, the underlying mechanisms and specific developmental programs regulated by the MAPK pathways have remained largel...

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Detalles Bibliográficos
Autores principales: Wang, Jingcai, Xia, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460833/
https://www.ncbi.nlm.nih.gov/pubmed/23060952
http://dx.doi.org/10.4161/cib.20216