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Regulation of ligand-independent Notch signal through intracellular trafficking

Notch signaling is an evolutionarily conserved mechanism that defines a key cell fate control mechanism in metazoans. Notch signaling relies on the surface interaction between the Notch receptor and membrane bound ligands in an apposing cell. In our recent study,(22) we uncover a non-canonical recep...

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Detalles Bibliográficos
Autores principales: Hori, Kazuya, Sen, Anindya, Kirchhausen, Tom, Artavanis-Tsakonas, Spyros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460843/
https://www.ncbi.nlm.nih.gov/pubmed/23060962
http://dx.doi.org/10.4161/cib.19995