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H(2)S-Releasing Aspirin Protects against Aspirin-Induced Gastric Injury via Reducing Oxidative Stress

The aim of this study was to examine the effect of ACS14, a hydrogen sulfide (H(2)S)-releasing derivative of aspirin (Asp), on Asp-induced gastric injury. Gastric hemorrhagic lesions were induced by intragastric administration of Asp (200 mg/kg, suspended in 0.5% carboxymethyl cellulose solutions) i...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Cui, Jie, Song, Cheng-Jie, Bian, Jin-Song, Sparatore, Anna, Soldato, Piero Del, Wang, Xin-Yu, Yan, Chang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460860/
https://www.ncbi.nlm.nih.gov/pubmed/23029468
http://dx.doi.org/10.1371/journal.pone.0046301