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The Epithelial Sodium Channel (ENaC) Establishes a Trafficking Vesicle Pool Responsible for Its Regulation

The epithelial sodium channel (ENaC) is the rate-limiting step for sodium reabsorption across tight epithelia. Cyclic-AMP (cAMP) stimulation promotes ENaC trafficking to the apical surface to increase channel number and transcellular Na(+) transport. Removal of corticosteroid supplementation in a cu...

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Detalles Bibliográficos
Autores principales: Edinger, Robert S., Bertrand, Carol A., Rondandino, Christine, Apodaca, Gerard A., Johnson, John P., Butterworth, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460899/
https://www.ncbi.nlm.nih.gov/pubmed/23029554
http://dx.doi.org/10.1371/journal.pone.0046593