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The Epithelial Sodium Channel (ENaC) Establishes a Trafficking Vesicle Pool Responsible for Its Regulation
The epithelial sodium channel (ENaC) is the rate-limiting step for sodium reabsorption across tight epithelia. Cyclic-AMP (cAMP) stimulation promotes ENaC trafficking to the apical surface to increase channel number and transcellular Na(+) transport. Removal of corticosteroid supplementation in a cu...
Autores principales: | Edinger, Robert S., Bertrand, Carol A., Rondandino, Christine, Apodaca, Gerard A., Johnson, John P., Butterworth, Michael B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460899/ https://www.ncbi.nlm.nih.gov/pubmed/23029554 http://dx.doi.org/10.1371/journal.pone.0046593 |
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