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Hypoxic Conditions Induce a Cancer-Like Phenotype in Human Breast Epithelial Cells

INTRODUCTION: Solid tumors are less oxygenated than their tissue of origin. Low intra-tumor oxygen levels are associated with worse outcome, increased metastatic potential and immature phenotype in breast cancer. We have reported that tumor hypoxia correlates to low differentiation status in breast...

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Detalles Bibliográficos
Autores principales: Vaapil, Marica, Helczynska, Karolina, Villadsen, René, Petersen, Ole W., Johansson, Elisabet, Beckman, Siv, Larsson, Christer, Påhlman, Sven, Jögi, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460905/
https://www.ncbi.nlm.nih.gov/pubmed/23029547
http://dx.doi.org/10.1371/journal.pone.0046543