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Interaction of Nuclease Colicins with Membranes: Insertion Depth Correlates with Bilayer Perturbation
BACKGROUND: Protein transport across cellular membranes is an important aspect of toxin biology. Escherichia coli cell killing by nuclease colicins occurs through DNA (DNases) or RNA (RNases) hydrolysis and to this end their cytotoxic domains require transportation across two sets of membranes. In o...
Autores principales: | Vankemmelbeke, Mireille, O′Shea, Paul, James, Richard, Penfold, Christopher N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460906/ https://www.ncbi.nlm.nih.gov/pubmed/23029560 http://dx.doi.org/10.1371/journal.pone.0046656 |
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