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An Accurate Prostate Cancer Prognosticator Using a Seven-Gene Signature Plus Gleason Score and Taking Cell Type Heterogeneity into Account

One of the major challenges in the development of prostate cancer prognostic biomarkers is the cellular heterogeneity in tissue samples. We developed an objective Cluster-Correlation (CC) analysis to identify gene expression changes in various cell types that are associated with progression. In the...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Xu, Shizhong, McClelland, Michael, Rahmatpanah, Farah, Sawyers, Anne, Jia, Zhenyu, Mercola, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460942/
https://www.ncbi.nlm.nih.gov/pubmed/23028830
http://dx.doi.org/10.1371/journal.pone.0045178