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An Accurate Prostate Cancer Prognosticator Using a Seven-Gene Signature Plus Gleason Score and Taking Cell Type Heterogeneity into Account
One of the major challenges in the development of prostate cancer prognostic biomarkers is the cellular heterogeneity in tissue samples. We developed an objective Cluster-Correlation (CC) analysis to identify gene expression changes in various cell types that are associated with progression. In the...
Autores principales: | Chen, Xin, Xu, Shizhong, McClelland, Michael, Rahmatpanah, Farah, Sawyers, Anne, Jia, Zhenyu, Mercola, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460942/ https://www.ncbi.nlm.nih.gov/pubmed/23028830 http://dx.doi.org/10.1371/journal.pone.0045178 |
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