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GPR54-Dependent Stimulation of Luteinizing Hormone Secretion by Neurokinin B in Prepubertal Rats

Kisspeptin, neurokinin B (NKB) and dynorphin A (Dyn) are coexpressed within KNDy neurons that project from the hypothalamic arcuate nucleus (ARC) to GnRH neurons and numerous other hypothalamic targets. Each of the KNDy neuropeptides has been implicated in regulating pulsatile GnRH/LH secretion. In...

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Detalles Bibliográficos
Autores principales: Grachev, Pasha, Li, Xiao Feng, Lin, Yuan Shao, Hu, Ming Han, Elsamani, Leena, Paterson, Stewart J., Millar, Robert P., Lightman, Stafford L., O’Byrne, Kevin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460954/
https://www.ncbi.nlm.nih.gov/pubmed/23028524
http://dx.doi.org/10.1371/journal.pone.0044344