Assessment of Algorithms for Inferring Positional Weight Matrix Motifs of Transcription Factor Binding Sites Using Protein Binding Microarray Data

The new technology of protein binding microarrays (PBMs) allows simultaneous measurement of the binding intensities of a transcription factor to tens of thousands of synthetic double-stranded DNA probes, covering all possible 10-mers. A key computational challenge is inferring the binding motif from...

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Detalles Bibliográficos
Autores principales: Orenstein, Yaron, Linhart, Chaim, Shamir, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460961/
https://www.ncbi.nlm.nih.gov/pubmed/23029415
http://dx.doi.org/10.1371/journal.pone.0046145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460961/
https://www.ncbi.nlm.nih.gov/pubmed/23029415
http://dx.doi.org/10.1371/journal.pone.0046145

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