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Coadministration of Lopinavir/Ritonavir and Rifampicin in HIV and Tuberculosis Co-Infected Adults in South Africa

BACKGROUND: In HIV-infected patients receiving rifampicin-based treatment for tuberculosis (TB), the dosage of lopinavir/ritonavir (LPV/r) is adjusted to prevent sub-therapeutic lopinavir concentrations. In this setting, South African clinicians were advised to administer super-boosted LPV/r (400 mg...

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Detalles Bibliográficos
Autores principales: Murphy, Richard A., Marconi, Vincent C., Gandhi, Rajesh T., Kuritzkes, Daniel R., Sunpath, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460963/
https://www.ncbi.nlm.nih.gov/pubmed/23028623
http://dx.doi.org/10.1371/journal.pone.0044793