Mutation in Phex Gene Predisposes BALB/c-Phex(Hyp-Duk)/Y Mice to Otitis Media

Genetic susceptibility underlying otitis media (OM) remains to be understood. We show in this study that mutation in Phex gene predisposes the BALB/c-Phex(Hyp-Duk)/Y (abbreviated Hyp-Duk/Y) mice to OM, which occurs at post-natal day 21 (P21) with an average penetrance of 73%. The OM was identified b...

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Detalles Bibliográficos
Autores principales: Han, Fengchan, Yu, Heping, Li, Ping, Zhang, Jiangping, Tian, Cong, Li, Hongbo, Zheng, Qing Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461009/
https://www.ncbi.nlm.nih.gov/pubmed/23028440
http://dx.doi.org/10.1371/journal.pone.0043010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461009/
https://www.ncbi.nlm.nih.gov/pubmed/23028440
http://dx.doi.org/10.1371/journal.pone.0043010

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