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Inhibition of Glioma Cell Lysosome Exocytosis Inhibits Glioma Invasion
Cancer cells invade by secreting enzymes that degrade the extracellular matrix and these are sequestered in lysosomal vesicles. In this study, the effects of the selective lysosome lysing drug GPN and the lysosome exocytosis inhibitor vacuolin-1 on lysosome exocytosis were studied to determine their...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461042/ https://www.ncbi.nlm.nih.gov/pubmed/23029308 http://dx.doi.org/10.1371/journal.pone.0045910 |