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Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications
BACKGROUND: Epigenetic remodelling of cancer cells is an attractive therapeutic strategy and distinct DNA hypomethylating agents (DHA) are being actively evaluated in patients with hemopoietic or solid tumours. However, no studies have investigated the modulation of gene expression profiles (GEP) in...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461156/ https://www.ncbi.nlm.nih.gov/pubmed/22910318 http://dx.doi.org/10.1038/bjc.2012.361 |