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Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications

BACKGROUND: Epigenetic remodelling of cancer cells is an attractive therapeutic strategy and distinct DNA hypomethylating agents (DHA) are being actively evaluated in patients with hemopoietic or solid tumours. However, no studies have investigated the modulation of gene expression profiles (GEP) in...

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Detalles Bibliográficos
Autores principales: Coral, S, Covre, A, JMG Nicolay, H, Parisi, G, Rizzo, A, Colizzi, F, Dalla Santa, S, Fonsatti, E, Fratta, E, Sigalotti, L, Maio, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461156/
https://www.ncbi.nlm.nih.gov/pubmed/22910318
http://dx.doi.org/10.1038/bjc.2012.361