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Phase I oncology trials incorporating patient choice of dose
BACKGROUND: Patients recruited in phase I oncology trials are often treated at doses lower than the maximum tolerated dose (MTD), and therefore may not receive the most efficacious dose available, despite their expectations to the contrary. This report investigates the consequences of allowing a pat...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461169/ https://www.ncbi.nlm.nih.gov/pubmed/22929891 http://dx.doi.org/10.1038/bjc.2012.378 |