Library-free Methylation Sequencing with Bisulfite Padlock Probes

We previously developed Bisulfite Padlock Probes (BSPPs) for the specific and parallel digital quantification of DNA methylation(1). Here we report the second-generation of BSPPs with a design algorithm to generate more efficient padlock probes, a library-free protocol that dramatically reduces the...

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Detalles Bibliográficos
Autores principales: Diep, Dinh, Plongthongkum, Nongluk, Gore, Athurva, Fung, Ho-Lim, Shoemaker, Robert, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461232/
https://www.ncbi.nlm.nih.gov/pubmed/22306810
http://dx.doi.org/10.1038/nmeth.1871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461232/
https://www.ncbi.nlm.nih.gov/pubmed/22306810
http://dx.doi.org/10.1038/nmeth.1871

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