Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson’s disease

Mitochondrial oxidant stress is widely viewed as critical to pathogenesis in Parkinson’s disease. But the origins of this stress are poorly defined. One possibility is that it arises from the metabolic demands associated with regenerative activity. To test this hypothesis, neurons in the dorsal moto...

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Detalles Bibliográficos
Autores principales: Goldberg, Joshua A., Guzman, Jaime N., Estep, Chad M., Ilijic, Ema, Kondapalli, Jyothisri, Sanchez-Padilla, Javier, Surmeier, D. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461271/
https://www.ncbi.nlm.nih.gov/pubmed/22941107
http://dx.doi.org/10.1038/nn.3209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461271/
https://www.ncbi.nlm.nih.gov/pubmed/22941107
http://dx.doi.org/10.1038/nn.3209

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