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Functional expression of a penicillin acylase from the extreme thermophile Thermus thermophilus HB27 in Escherichia coli

BACKGROUND: Penicillin acylases (PACs) are enzymes of industrial relevance in the manufacture of β-lactam antibiotics. Development of a PAC with a longer half-life under the reaction conditions used is essential for the improvement of the operational stability of the process. A gene encoding a homol...

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Detalles Bibliográficos
Autores principales: Torres, Leticia L, Ferreras, Eloy R, Cantero, Ángel, Hidalgo, Aurelio, Berenguer, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461476/
https://www.ncbi.nlm.nih.gov/pubmed/22876915
http://dx.doi.org/10.1186/1475-2859-11-105