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Functional expression of a penicillin acylase from the extreme thermophile Thermus thermophilus HB27 in Escherichia coli
BACKGROUND: Penicillin acylases (PACs) are enzymes of industrial relevance in the manufacture of β-lactam antibiotics. Development of a PAC with a longer half-life under the reaction conditions used is essential for the improvement of the operational stability of the process. A gene encoding a homol...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461476/ https://www.ncbi.nlm.nih.gov/pubmed/22876915 http://dx.doi.org/10.1186/1475-2859-11-105 |