Cargando…

Cortical dynein is critical for proper spindle positioning in human cells

Correct spindle positioning is fundamental for proper cell division during development and in stem cell lineages. Dynein and an evolutionarily conserved ternary complex (nuclear mitotic apparatus protein [NuMA]–LGN–Gα in human cells and LIN-5–GPR-1/2–Gα in Caenorhabditis elegans) are required for co...

Descripción completa

Detalles Bibliográficos
Autores principales: Kotak, Sachin, Busso, Coralie, Gönczy, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461507/
https://www.ncbi.nlm.nih.gov/pubmed/23027904
http://dx.doi.org/10.1083/jcb.201203166