Transcription of the Tumor Suppressor Genes p53 and RB in Lymphocytes from Patients with Chronic Kidney Disease: Evidence of Molecular Senescence?

Patients suffering from renal failure exhibit an impaired immune system function. We wanted to investigate the transcription of the tumor suppressor genes p53 and RB to record, if these cells could be stimulated in vitro in order to divide, after the addition of antigenic and inflammatory factors. T...

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Detalles Bibliográficos
Autores principales: Kordinas, Vasileios, Nicolaou, Chryssoula, Tsirpanlis, George, Ioannidis, Anastasios, Bersimis, Sotiris, Sabanis, Nikos, Fragou, Eleni, Tsiolaki, Konstantina, Chatzipanagiotou, Stylianos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461626/
https://www.ncbi.nlm.nih.gov/pubmed/23050148
http://dx.doi.org/10.1155/2012/154397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461626/
https://www.ncbi.nlm.nih.gov/pubmed/23050148
http://dx.doi.org/10.1155/2012/154397

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