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Waldenström's macroglobulinemia harbors a unique proteome where Ku70 is severely underexpressed as compared with other B-lymphoproliferative disorders

Waldenström's macroglobulinemia (WM) is a clonal B-cell lymphoproliferative disorder (LPD) of post-germinal center nature. Despite the fact that the precise molecular pathway(s) leading to WM remain(s) to be elucidated, a hallmark of the disease is the absence of the immunoglobulin heavy chain...

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Detalles Bibliográficos
Autores principales: Perrot, A, Pionneau, C, Azar, N, Baillou, C, Lemoine, F M, Leblond, V, Merle-Béral, H, Béné, M-C, Herbrecht, R, Bahram, S, Vallat, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461705/
https://www.ncbi.nlm.nih.gov/pubmed/22961060
http://dx.doi.org/10.1038/bcj.2012.35