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Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms

Aberrant reactivation of hedgehog (Hh) signaling has been described in a wide variety of human cancers including cancer stem cells. However, involvement of the Hh-signaling system in the bone marrow (BM) microenvironment during the development of myeloid neoplasms is unknown. In this study, we asses...

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Detalles Bibliográficos
Autores principales: Kobune, M, Iyama, S, Kikuchi, S, Horiguchi, H, Sato, T, Murase, K, Kawano, Y, Takada, K, Ono, K, Kamihara, Y, Hayashi, T, Miyanishi, K, Sato, Y, Takimoto, R, Kato, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461706/
https://www.ncbi.nlm.nih.gov/pubmed/22961059
http://dx.doi.org/10.1038/bcj.2012.36