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Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms
Aberrant reactivation of hedgehog (Hh) signaling has been described in a wide variety of human cancers including cancer stem cells. However, involvement of the Hh-signaling system in the bone marrow (BM) microenvironment during the development of myeloid neoplasms is unknown. In this study, we asses...
Autores principales: | Kobune, M, Iyama, S, Kikuchi, S, Horiguchi, H, Sato, T, Murase, K, Kawano, Y, Takada, K, Ono, K, Kamihara, Y, Hayashi, T, Miyanishi, K, Sato, Y, Takimoto, R, Kato, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461706/ https://www.ncbi.nlm.nih.gov/pubmed/22961059 http://dx.doi.org/10.1038/bcj.2012.36 |
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