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Tug of war in the haematopoietic stem cell niche: do myeloma plasma cells compete for the HSC niche?

In the adult mammal, normal haematopoiesis occurs predominantly in the bone marrow, where primitive haematopoietic stem cells (HSC) and their progeny reside in specialised microenvironments. The bone marrow microenvironment contains specific anatomical areas (termed niches) that are highly specialis...

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Detalles Bibliográficos
Autores principales: Noll, J E, Williams, S A, Purton, L E, Zannettino, A C W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461708/
https://www.ncbi.nlm.nih.gov/pubmed/22983434
http://dx.doi.org/10.1038/bcj.2012.38