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Dynamics of a Cytokine Storm

Six volunteers experienced severe inflammatory response during the Phase I clinical trial of a monoclonal antibody that was designed to stimulate a regulatory T cell response. Soon after the trial began, each volunteer experienced a “cytokine storm”, a dramatic increase in cytokine concentrations. T...

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Detalles Bibliográficos
Autores principales: Yiu, Hao Hong, Graham, Andrea L., Stengel, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462188/
https://www.ncbi.nlm.nih.gov/pubmed/23049677
http://dx.doi.org/10.1371/journal.pone.0045027