A Peptidic Unconjugated GRP78/BiP Ligand Modulates the Unfolded Protein Response and Induces Prostate Cancer Cell Death

The molecular chaperone GRP78/BiP is a key regulator of protein folding in the endoplasmic reticulum, and it plays a pivotal role in cancer cell survival and chemoresistance. Inhibition of its function has therefore been an important strategy for inhibiting tumor cell growth in cancer therapy. Previ...

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Detalles Bibliográficos
Autores principales: Maddalo, Danilo, Neeb, Antje, Jehle, Katja, Schmitz, Katja, Muhle-Goll, Claudia, Shatkina, Liubov, Walther, Tamara Vanessa, Bruchmann, Anja, Gopal, Srinivasa M., Wenzel, Wolfgang, Ulrich, Anne S., Cato, Andrew C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462190/
https://www.ncbi.nlm.nih.gov/pubmed/23049684
http://dx.doi.org/10.1371/journal.pone.0045690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462190/
https://www.ncbi.nlm.nih.gov/pubmed/23049684
http://dx.doi.org/10.1371/journal.pone.0045690

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