A Peptidic Unconjugated GRP78/BiP Ligand Modulates the Unfolded Protein Response and Induces Prostate Cancer Cell Death

The molecular chaperone GRP78/BiP is a key regulator of protein folding in the endoplasmic reticulum, and it plays a pivotal role in cancer cell survival and chemoresistance. Inhibition of its function has therefore been an important strategy for inhibiting tumor cell growth in cancer therapy. Previ...

Descripción completa

Detalles Bibliográficos
Autores principales: Maddalo, Danilo, Neeb, Antje, Jehle, Katja, Schmitz, Katja, Muhle-Goll, Claudia, Shatkina, Liubov, Walther, Tamara Vanessa, Bruchmann, Anja, Gopal, Srinivasa M., Wenzel, Wolfgang, Ulrich, Anne S., Cato, Andrew C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462190/
https://www.ncbi.nlm.nih.gov/pubmed/23049684
http://dx.doi.org/10.1371/journal.pone.0045690

Ejemplares similares

Ejemplares similares