Cargando…

Modeling and Experimental Methods to Probe the Link between Global Transcription and Spatial Organization of Chromosomes

Genomes are spatially assembled into chromosome territories (CT) within the nucleus of living cells. Recent evidences have suggested associations between three-dimensional organization of CTs and the active gene clusters within neighboring CTs. These gene clusters are part of signaling networks shar...

Descripción completa

Detalles Bibliográficos
Autores principales: Iyer, K. Venkatesan, Maharana, Shovamayee, Gupta, Soumya, Libchaber, Albert, Tlusty, Tsvi, Shivashankar, G. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462193/
https://www.ncbi.nlm.nih.gov/pubmed/23049710
http://dx.doi.org/10.1371/journal.pone.0046628