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Modeling and Experimental Methods to Probe the Link between Global Transcription and Spatial Organization of Chromosomes
Genomes are spatially assembled into chromosome territories (CT) within the nucleus of living cells. Recent evidences have suggested associations between three-dimensional organization of CTs and the active gene clusters within neighboring CTs. These gene clusters are part of signaling networks shar...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462193/ https://www.ncbi.nlm.nih.gov/pubmed/23049710 http://dx.doi.org/10.1371/journal.pone.0046628 |