Serotonin transporter activity of imidazolidine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives in aspect of their acid–base properties

Affinities of arylpiperazinylalkyl derivatives of imidazo[2,1-f]purine-2,4-dione and imidazolidine-2,4-dione for serotonin transporter and their acid–base properties were evaluated. The dissociation constant (pK (a)) of compounds 1–22 were determinated by potentiometric titration and calculated usin...

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Detalles Bibliográficos
Autores principales: Zagórska, Agnieszka, Czopek, Anna, Pawłowski, Maciej, Dybała, Małgorzata, Siwek, Agata, Nowak, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462310/
https://www.ncbi.nlm.nih.gov/pubmed/23049232
http://dx.doi.org/10.1007/s00044-011-9883-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462310/
https://www.ncbi.nlm.nih.gov/pubmed/23049232
http://dx.doi.org/10.1007/s00044-011-9883-y

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