HSP70 and HSP90 Differentially Regulate Translocation of Extracellular Antigen to the Cytosol for Cross-Presentation

Antigens (Ag) from cancer or virus-infected cells must be internalized by dendritic cells (DCs) to be presented to CD8(+) T cells, which eventually differentiate into Ag-specific cytotoxic T lymphocytes (CTLs) that destroy cancer cells and infected cells. This pathway is termed cross-presentation an...

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Detalles Bibliográficos
Autores principales: Kato, Yu, Kajiwara, Chiaki, Ishige, Ikuo, Mizukami, Shusaku, Yamazaki, Chihiro, Eikawa, Shingo, Kakimi, Kazuhiro, Udono, Heiichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462380/
https://www.ncbi.nlm.nih.gov/pubmed/23050124
http://dx.doi.org/10.1155/2012/745962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462380/
https://www.ncbi.nlm.nih.gov/pubmed/23050124
http://dx.doi.org/10.1155/2012/745962

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