Development of inflammation-induced hyperalgesia and allodynia is associated with the upregulation of extrasynaptic AMPA receptors in tonically firing lamina II dorsal horn neurons

Persistent peripheral inflammation changes AMPA receptor (AMPAR) trafficking in dorsal horn neurons by promoting internalization of GluR2-containing, Ca(2+)-impermeable AMPARs from the synapses and by increasing insertion of GluR1-containing, Ca(2+)-permeable AMPARs in extrasynaptic plasma membrane....

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Detalles Bibliográficos
Autores principales: Kopach, Olga, Viatchenko-Karpinski, Viacheslav, Belan, Pavel, Voitenko, Nana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462428/
https://www.ncbi.nlm.nih.gov/pubmed/23060815
http://dx.doi.org/10.3389/fphys.2012.00391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462428/
https://www.ncbi.nlm.nih.gov/pubmed/23060815
http://dx.doi.org/10.3389/fphys.2012.00391

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