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Solution structure of the core SMN–Gemin2 complex

In humans, assembly of spliceosomal snRNPs (small nuclear ribonucleoproteins) begins in the cytoplasm where the multi-protein SMN (survival of motor neuron) complex mediates the formation of a seven-membered ring of Sm proteins on to a conserved site of the snRNA (small nuclear RNA). The SMN complex...

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Detalles Bibliográficos
Autores principales: Sarachan, Kathryn L., Valentine, Kathleen G., Gupta, Kushol, Moorman, Veronica R., Gledhill, John M., Bernens, Matthew, Tommos, Cecilia, Wand, A. Joshua, Van Duyne, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462613/
https://www.ncbi.nlm.nih.gov/pubmed/22607171
http://dx.doi.org/10.1042/BJ20120241