A novel dic (17;18) (p13.1;q11.2) with loss of TP53 and BCR/ABL rearrangement in an Imatinib resistant chronic myeloid leukemia

BACKGROUND: The so-called Philadelphia (Ph) chromosome is present in more than 90% of chronic myeloid leukemia (CML) cases. It results in juxtaposition of the 5′ part of the BCR gene on chromosome 22 to the 3′ part of the ABL gene on chromosome 9. Since the majority of CML cases are currently treate...

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Detalles Bibliográficos
Autores principales: Al-achkar, Walid, Wafa, Abdulsamad, Moassass, Faten, Othman, Moneeb Abdullah Kassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462673/
https://www.ncbi.nlm.nih.gov/pubmed/22901309
http://dx.doi.org/10.1186/1755-8166-5-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462673/
https://www.ncbi.nlm.nih.gov/pubmed/22901309
http://dx.doi.org/10.1186/1755-8166-5-36

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