Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus

BACKGROUND: Neuroinflammation and protein accumulation are characteristic hallmarks of both normal aging and age-related neurodegenerative diseases. However, the relationship between these factors in neurodegenerative processes is poorly understood. We have previously shown that proteasome inhibitio...

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Detalles Bibliográficos
Autores principales: Pintado, Cristina, Gavilán, María P, Gavilán, Elena, García-Cuervo, Luisa, Gutiérrez, Antonia, Vitorica, Javier, Castaño, Angélica, Ríos, Rosa M, Ruano, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462674/
https://www.ncbi.nlm.nih.gov/pubmed/22559833
http://dx.doi.org/10.1186/1742-2094-9-87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462674/
https://www.ncbi.nlm.nih.gov/pubmed/22559833
http://dx.doi.org/10.1186/1742-2094-9-87

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