Neutralisation of Peritoneal IL-17A Markedly Improves the Prognosis of Severe Septic Mice by Decreasing Neutrophil Infiltration and Proinflammatory Cytokines

PURPOSE: The current study aimed to elucidate the role of peritoneal fluid IL-17A in septic mice, and the effects of intraperitoneal or intravenous blockade of the IL-17A pathway by anti-IL17A antibody on survival, plasma, and peritoneal cavity cytokine profile in a murine caecal ligation and punctu...

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Detalles Bibliográficos
Autores principales: Li, Jinbao, Zhang, Yan, Lou, Jingsheng, Zhu, Jiali, He, Miaoxia, Deng, Xiaoming, Cai, Zailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462769/
https://www.ncbi.nlm.nih.gov/pubmed/23056325
http://dx.doi.org/10.1371/journal.pone.0046506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462769/
https://www.ncbi.nlm.nih.gov/pubmed/23056325
http://dx.doi.org/10.1371/journal.pone.0046506

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