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Oligomerization of Clostridium perfringens Epsilon Toxin Is Dependent upon Caveolins 1 and 2

Evidence from multiple studies suggests that Clostridium perfringens ε-toxin is a pore-forming toxin, assembling into oligomeric complexes in the plasma membrane of sensitive cells. In a previous study, we used gene-trap mutagenesis to identify mammalian factors contributing to toxin activity, inclu...

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Detalles Bibliográficos
Autores principales: Fennessey, Christine M., Sheng, Jinsong, Rubin, Donald H., McClain, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462777/
https://www.ncbi.nlm.nih.gov/pubmed/23056496
http://dx.doi.org/10.1371/journal.pone.0046866