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Oligomerization of Clostridium perfringens Epsilon Toxin Is Dependent upon Caveolins 1 and 2
Evidence from multiple studies suggests that Clostridium perfringens ε-toxin is a pore-forming toxin, assembling into oligomeric complexes in the plasma membrane of sensitive cells. In a previous study, we used gene-trap mutagenesis to identify mammalian factors contributing to toxin activity, inclu...
Autores principales: | Fennessey, Christine M., Sheng, Jinsong, Rubin, Donald H., McClain, Mark S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462777/ https://www.ncbi.nlm.nih.gov/pubmed/23056496 http://dx.doi.org/10.1371/journal.pone.0046866 |
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