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Disruption of 3D MCF-12A Breast Cell Cultures by Estrogens – An In Vitro Model for ER-Mediated Changes Indicative of Hormonal Carcinogenesis

INTRODUCTION: Estrogens regulate the proliferation of normal and neoplastic breast epithelium. Although the intracellular mechanisms of estrogens in the breast are largely understood, little is known about how they induce changes in the structure of the mammary epithelium, which are characteristic o...

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Detalles Bibliográficos
Autores principales: Marchese, Stephanie, Silva, Elisabete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462778/
https://www.ncbi.nlm.nih.gov/pubmed/23056216
http://dx.doi.org/10.1371/journal.pone.0045767