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Selection of DNA Aptamers against Glioblastoma Cells with High Affinity and Specificity

BACKGROUND: Glioblastoma is the most common and most lethal form of brain tumor in human. Unfortunately, there is still no effective therapy to this fatal disease and the median survival is generally less than one year from the time of diagnosis. Discovery of ligands that can bind specifically to th...

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Detalles Bibliográficos
Autores principales: Kang, Dezhi, Wang, Jiangjie, Zhang, Weiyun, Song, Yanling, Li, Xilan, Zou, Yuan, Zhu, Mingtao, Zhu, Zhi, Chen, Fuyong, Yang, Chaoyong James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462804/
https://www.ncbi.nlm.nih.gov/pubmed/23056171
http://dx.doi.org/10.1371/journal.pone.0042731