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Length Bias Correction in Gene Ontology Enrichment Analysis Using Logistic Regression

When assessing differential gene expression from RNA sequencing data, commonly used statistical tests tend to have greater power to detect differential expression of genes encoding longer transcripts. This phenomenon, called “length bias”, will influence subsequent analyses such as Gene Ontology enr...

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Detalles Bibliográficos
Autores principales: Mi, Gu, Di, Yanming, Emerson, Sarah, Cumbie, Jason S., Chang, Jeff H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462807/
https://www.ncbi.nlm.nih.gov/pubmed/23056249
http://dx.doi.org/10.1371/journal.pone.0046128