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Chibby suppresses growth of human SW480 colon adenocarcinoma cells through inhibition of β-catenin signaling
The canonical Wnt signaling pathway is crucial for embryonic development and adult tissue homeostasis. Activating mutations in the Wnt pathway are frequently associated with the pathogenesis of various types of cancer, particularly colon cancer. Upon Wnt stimulation, β-catenin plays a central role a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463480/ https://www.ncbi.nlm.nih.gov/pubmed/22651859 http://dx.doi.org/10.1186/1750-2187-7-6 |