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Unique C2V3 Sequence in HIV-1 Envelope Obtained from Broadly Neutralizing Plasma of a Slow Progressing Patient Conferred Enhanced Virus Neutralization

Broadly neutralizing antibodies to HIV-1 usually develops in chronic infections. Here, we examined the basis of enhanced sensitivity of an env clone amplified from cross neutralizing plasma of an antiretroviral naïve chronically infected Indian patient (ID50 >600-fold higher compared to other aut...

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Detalles Bibliográficos
Autores principales: Ringe, Rajesh, Das, Lipsa, Choudhary, Ipsita, Sharma, Deepak, Paranjape, Ramesh, Chauhan, Virander Singh, Bhattacharya, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463516/
https://www.ncbi.nlm.nih.gov/pubmed/23056416
http://dx.doi.org/10.1371/journal.pone.0046713